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Doctors who study or treat Alzheimer's disease and its early clinical stages (mild cognitive impairment, MCI) are focused on the obvious problems with short-term memory. However, a new study suggests that people with whom later develop Alzheimer's disease may have problems much earlier, in the processing of semantic information or data based on previous knowledge, which could have great significance in the way these patients are functioning in everyday life.
Terry Goldberg, Ph.. D, professor owl canisters of psychiatry and behaviorism in the Medical School of North Coast-LIJ and Hofstra owl canisters ua neurokogniciju Director of the Center for Research of Alzheimer's disease and memory owl canisters disorders at the Institute for Medical Research in Manhasset Feinstein in New York, said that doctors have noticed a variety of cognitive disorders in patients with MCI-operation, but that they have not been systematically studied. A large number of experts noted that some of the patients and the simplest tasks extremely confusing. In this latest study, published in ovomjesečnome American Journal of Psychiatry, owl canisters used cleverly designed tests to analyze the ability owl canisters of individuals in the processing of semantic information.
To test the system semantic processing, Dr. Goldberg and his colleagues should have a task that does not involve verbal response. It would be confusing and the results would be more difficult to interpret. They decided to use size to test the ability of a person to using semantic information to make a finding on two opposed definitions. Doctor Goldberg explained: "If you ask someone what's more, key or ant, will respond more slowly than if you're wondering whether higher or house key." The greater the difference in size between the two things, that the person was healthy or not , quickly recognize the difference and respond.
The study included 25 patients with mild cognitive impairment (MCI), 27 with Alzheimer's disease and 70 people without cognitive difficulties. They found that there are significant differences between healthy controls and patients with MCI-operation and Alzheimer's. Doctor Goldberg concluded that the results indicate problems in semantic data processing. This is most visible when the patients with MCI-operation and Alzheimer's disease cope with the task with slight differences in size.
Then they complicate the task of showing patients images of small ants and big houses or large ants and small houses. This time, patients with MCI-operation with Alzheimer's disease without problems solved the first part of the test - when they were asked what is more, they chose a house, not an ant. But if the pictures did not reflect owl canisters reality - a big ant acted much like a small house - were confused, answered incorrectly or took them longer to respond.
Would damage to Semantically system influenced the everyday functions? To answer this question, researchers have turned to UCSD scale for assessing owl canisters the use of skills, tools which are used in patients with MCI-operation and Alzheimer's disease, which is normally used to determine the functional deficiencies in patients with schizophrenia. The test examines a person's ability to perform complex checks or to organize a trip to the zoo for cold days.
It's a good way to check if someone has a problem with the semantic knowledge. Semantic processing takes place in the left temporal lobe. "The semantic system is organized as a network that reflects the various types of connections and associations," the researchers said in a study. "Semantic Data and knowledge owl canisters acquired in the larger spaces and often through owl canisters a large number of repetitions and do not reflect owl canisters what has recently been adopted."
Doctor Goldberg says that this discovery is extremely important because it might be possible training to strengthen the ties that arise in semantic processing. "This indicates that patients slows semantic, not epizodičko memory," owl canisters says Goldberg. Patients will continue to observe in order to determine whether the semantic exacerbate problems as the disease progresses.
In its additional article, David P. Salmon, Ph.D., Department of Neuroscience at the University of California, says that "deficiencies in Semantically memory, which this study demonstrated, confirming the suspicion that in patients with mild cognitive impairment owl canisters amnestic type leads to mild cognitive deterioration. Since the task did not require problematic remembering, remembering certain words or linguistic structures, it can be concluded that these shortcomings reflect the early and gradual loss of integrity of semantic knowledge
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